Andrew J Souers: search on Z-Library

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1

Air Gaps, Size Effect, and Corner-Turning in Ambient LX-17

P. Clark Souers, Andrew Hernandez, Chris Cabacungan, Raul Garza, Lisa Lauderbach, Sen-Ben Liao, Peter Vitello

Journal:

Propellants, Explosives, Pyrotechnics

Year:

2009

Language:

english

File:

PDF, 446 KB

english, 2009

2

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Souers, Andrew J, Leverson, Joel D, Boghaert, Erwin R, Ackler, Scott L, Catron, Nathaniel D, Chen, Jun, Dayton, Brian D, Ding, Hong, Enschede, Sari H, Fairbrother, Wayne J, Huang, David C S, Hymowitz,

Journal:

Nature Medicine

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

3

Clearance of therapyâinduced senescent tumor cells by the senolytic ABTâ263 via interference with BCLâX L âBAX Interaction

Saleh, Tareq, Carpenter, Valerie J., TyutyunykâMassey, Liliya, Murray, Graeme, Leverson, Joel D., Souers, Andrew J., Alotaibi, Moureq R., Faber, Anthony, Reed, Jason, Harada, Hisashi, Gewirtz, David

Journal:

Molecular Oncology

Year:

2020

File:

PDF, 80.37 MB

2020

4

Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonists

Anil Vasudevan, Andrew J. Souers, Jennifer C. Freeman, Mary K. Verzal, Ju Gao, Mathew M. Mulhern, Derek Wodka, John K. Lynch, Kenneth M. Engstrom, Seble H. Wagaw, Sevan Brodjian, Brian Dayton, Doug H.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 179 KB

english, 2005

5

From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors

Ashkenazi, Avi, Fairbrother, Wayne J., Leverson, Joel D., Souers, Andrew J.

Journal:

Nature Reviews Drug Discovery

Year:

2017

Language:

english

File:

PDF, 752 KB

english, 2017

6

Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein

Petros, Andrew M., Swann, Steven L., Song, Danying, Swinger, Kerren, Park, Chang, Zhang, Haichao, Wendt, Michael D., Kunzer, Aaron R., Souers, Andrew J., Sun, Chaohong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 4.97 MB

english, 2014

7

Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 2

Anil Vasudevan, Dariusz Wodka, Mary K. Verzal, Andrew J. Souers, Ju Gao, Sevan Brodjian, Dennis Fry, Brian Dayton, Kennan C. Marsh, Lisa E. Hernandez, Christopher A. Ogiela, Christine A. Collins, Phil

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 266 KB

english, 2004

8

Identification of diamino chromone-2-carboxamides as MCHr1 antagonists with minimal hERG channel activity

Andrew S. Judd, Andrew J. Souers, Dariusz Wodka, Gang Zhao, Mathew M. Mulhern, Rajesh R. Iyengar, Ju Gao, John K. Lynch, Jennifer C. Freeman, H. Douglas Falls, Sevan Brodjian, Brian D. Dayton, Regina

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 219 KB

english, 2007

9

Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 3

Andrew J. Souers, Dariusz Wodka, Ju Gao, Jared C. Lewis, Anil Vasudevan, Sevan Brodjian, Brian Dayton, Christopher A. Ogiela, Dennis Fry, Lisa E. Hernandez, Kennan C. Marsh, Christine A. Collins, Phil

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 268 KB

english, 2004

10

Immunohistochemistry Practices of Cytopathology Laboratories: A Survey of Participants in the College of American Pathologists Nongynecologic Cytopathology Education Program

Fischer, Andrew H., Schwartz, Mary R., Moriarty, Ann T., Wilbur, David C., Souers, Rhona, Fatheree, Lisa, Booth, Christine N., Clayton, Amy C., Kurtyz, Daniel F. I., Padmanabhan, Vijayalakshmi, Crothe

Journal:

Archives of Pathology & Laboratory Medicine

Year:

2014

Language:

english

File:

PDF, 86 KB

english, 2014

11

Synthesis and Evaluation of 2-Amino-8-alkoxy Quinolines as MCHr1 Antagonists. Part 1.

Andrew J. Souers, et al. et al.

Journal:

Year:

2004

File:

PDF, 7 KB

2004

12

Asymmetric Synthesis of a C-3 Substituted Pipecolic Acid

Souers, Andrew J., Ellman, Jonathan A.

Journal:

Journal of Organic Chemistry

Year:

2000

Language:

english

File:

PDF, 47 KB

english, 2000

13

Process Development of a Diacyl Glycerolacyltransferase-1 Inhibitor

Ravn, Matthew M., Wagaw, Seble H., Engstrom, Kenneth M., Mei, Jianzhang, Kotecki, Brian, Souers, Andrew J., Kym, Philip R., Judd, Andrew S., Zhao, Gang

Journal:

Organic Process Research & Development

Year:

2010

Language:

english

File:

PDF, 326 KB

english, 2010

14

Lead Optimization Strategies and Tactics Applied to the Discovery of Melanin Concentrating Hormone Receptor 1 Antagonists

Kym, Philip, Judd, Andrew, Lynch, John, Iyengar, Rajesh, Vasudevan, Anil, Souers, Andrew

Journal:

Current Topics in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 650 KB

english, 2007

15

The Tahoe Study: Bias in the Interpretation of Papanicolaou Test Results When Human Papillomavirus Status Is Known

Moriarty, Ann T., Nayar, Ritu, Arnold, Terry, Gearries, Lisa, Renshaw, Andrew, Thomas, Nicole, Souers, Rhona

Journal:

Archives of Pathology & Laboratory Medicine

Year:

2014

Language:

english

File:

PDF, 80 KB

english, 2014

16

ChemInform Abstract: β-Turn Mimetic Library Synthesis: Scaffolds and Applications

Andrew J. Souers, Jonathan A. Ellman

Journal:

Year:

2001

File:

PDF, 28 KB

2001

17

Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity

Andrew J. Souers, Ju Gao, Dariusz Wodka, Andrew S. Judd, Mathew M. Mulhern, James J. Napier, Michael E. Brune, Eugene N. Bush, Sevan J. Brodjian, Brian D. Dayton, Robin Shapiro, Lisa E. Hernandez, Ken

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 282 KB

english, 2005

18

Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: The effects of chirality on substituted indan-1-ylamines

Andrew J. Souers, Rajesh R. Iyengar, Andrew S. Judd, David W.A. Beno, Ju Gao, Gang Zhao, Michael E. Brune, James J. Napier, Mathew M. Mulhern, John K. Lynch, Jennifer C. Freeman, Dariusz Wodka, Chong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 200 KB

english, 2007

19

A cascade reaction sequence en route to 7-substituted 2-aminopyrrolo[1,2-a]pyrimidine-4,6-diones and the corresponding acrylic acid derivatives

Ju Gao, Rodger F. Henry, Thomas G. Pagano, Richard W. Duerst, Andrew J. Souers

Journal:

Tetrahedron Letters

Year:

2007

Language:

english

File:

PDF, 189 KB

english, 2007

20

β-Turn mimetic library synthesis: scaffolds and applications

Andrew J. Souers, Jonathan A. Ellman

Journal:

Year:

2001

Language:

english

File:

PDF, 480 KB

english, 2001

21

Toward Standard Controls for Her2 Immunohistochemistry

Sundling, Kaitlin, Fischer, Andrew, Kurtycz, Daniel, Schinstine, Malcolm, Swanson, Paul, Witt, Benjamin, Souers, Rhona, Crothers, Barbara A.

Journal:

Journal of the American Society of Cytopathology

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

22

Genetic Biomarkers Of Sensitivity and Resistance to Venetoclax Monotherapy in Patients With Relapsed Acute Myeloid Leukemia

Chyla, Brenda, Daver, Naval, Doyle, Kelly, McKeegan, Evelyn, Huang, Xin, Ruvolo, Vivian, Wang, Zixing, Chen, Ken, Souers, Andrew, Leverson, Joel, Potluri, Jalaja, Boghaert, Erwin, Bhathena, Anahita, K

Journal:

American Journal of Hematology

Year:

2018

Language:

english

File:

PDF, 892 KB

english, 2018

23

An evaluation of 3,4-methylenedioxy phenyl replacements in the aminopiperidine chromone class of MCHr1 antagonists

Rajesh R. Iyengar, John K. Lynch, Mathew M. Mulhern, Andrew S. Judd, Jennifer C. Freeman, Ju Gao, Andrew J. Souers, Gang Zhao, Dariusz Wodka, H. Doug Falls, Sevan Brodjian, Brian D. Dayton, Regina M.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 211 KB

english, 2007

24

Identification of aminopiperidine benzamides as MCHr1 antagonists

Anil Vasudevan, Mary K. Verzal, Derek Wodka, Andrew J. Souers, Christopher Blackburn, Jennifer Lee Che, Sujen Lai, Sevan Brodjian, Doug H. Falls, Brian D. Dayton, Elizabeth Govek, Tom Daniels, Brad Ge

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 244 KB

english, 2005

25

Performance Differences Between Conventional Smears and Liquid-Based Preparations of Thyroid Fine-Needle Aspiration Samples: Analysis of 47 076 Responses in the College of American Pathologists Interlaboratory Comparison Program in Non-Gynecologic Cytology

Fischer, Andrew H., Clayton, Amy C., Bentz, Joel S., Wasserman, Patricia G., Henry, Michael R., Souers, Rhona J., Moriarty, Ann T.

Journal:

Archives of Pathology & Laboratory Medicine

Year:

2013

Language:

english

File:

PDF, 1.56 MB

english, 2013

26

Lead Optimization of Melanin Concentrating Hormone Receptor 1 Antagonists with low hERG Channel Activity

Judd, Andrew, Souers, Andrew, Kym, Philip

Journal:

Current Topics in Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 142 KB

english, 2008

27

Microwave-Assisted C—H Bond Activation: A Rapid Entry into Functionalized Heterocycles.

Kian L. Tan, Anil Vasudevan, Robert G. Bergman, Jonathan A. Ellman, Andrew J. Souers

Journal:

Year:

2003

File:

PDF, 129 KB

2003

28

Optimization of a somatostatin mimetic via constrained amino acid and backbone incorporation

Andrew J. Souers, Asa Rosenquist, Emma M. Jarvie, Mark Ladlow, Wasyl Feniuk, Jonathan A. Ellman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 150 KB

english, 2000

29

Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1

Andrew J. Souers, Dariusz Wodka, Ju Gao, Jared C. Lewis, Anil Vasudevan, Robert Gentles, Sevan Brodjian, Brian Dayton, Christopher A. Ogiela, Dennis Fry, Lisa E. Hernandez, Kennan C. Marsh, Christine

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 281 KB

english, 2004

30

Electrophysiologic Characterization of a Complex hERG Channel Activator

Su, Zhi, Limberis, James, Souers, Andrew, Kym, Philip, Mikhail, Ann, Houseman, Kathryn, Diaz, Gilbert, Martin, Ruth L., Cox, Bryan F., Gintant, Gary A.

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 42 KB

english, 2009

31

Preparation of Enantioenriched α-Bromo Acids Incorporating Diverse Functionality

Souers, Andrew J., Schürer, Stephan, Kwack, Heemun, Virgilio, Alex A., Ellman, Jonathan A.

Journal:

Year:

1999

Language:

english

File:

PDF, 42 KB

english, 1999

32

Novel inhibitors of α4β1 integrin receptor interactions through library synthesis and screening

Andrew J Souers, Alex A Virgilio, Stephan S Schürer, Jonathan A Ellman, Timothy P Kogan, Henry E West, Wendy Ankener, Peter Vanderslice

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 275 KB

english, 1998

33

Synthesis and Crystal Structure of a Unique and Homochiral N,S -Bonded N,N ‘ -Bis( tert -butanesulfinyl)amidinate Rhodium(I) Complex

Souers, Andrew J., Owens, Timothy D., Oliver, Allen G., Hollander, Frederick J., Ellman, Jonathan A.

Journal:

Inorganic Chemistry

Year:

2001

Language:

english

File:

PDF, 42 KB

english, 2001

34

Compounds That Activate the Mouse Melanocortin-1 Receptor Identified by Screening a Small Molecule Library Based upon the β-Turn

Haskell-Luevano, Carrie, Rosenquist, Åsa, Souers, Andrew, Khong, Kathy C., Ellman, Jonathon A., Cone, Roger D.

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 187 KB

english, 1999

35

Discovery and Characterization of Aminopiperidinecoumarin Melanin Concentrating Hormone Receptor 1 Antagonists

Kym, Philip R., Iyengar, Rajesh, Souers, Andrew J., Lynch, John K., Judd, Andrew S., Gao, Ju, Freeman, Jennifer, Mulhern, Mathew, Zhao, Gang, Vasudevan, Anil, Wodka, Dariusz, Blackburn, Christopher, B

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 102 KB

english, 2005

36

In vivo efficacy of acyl CoA: Diacylglycerol acyltransferase (DGAT) 1 inhibition in rodent models of postprandial hyperlipidemia

Andrew J. King, Jason A. Segreti, Kelly J. Larson, Andrew J. Souers, Philip R. Kym, Regina M. Reilly, Christine A. Collins, Martin J. Voorbach, Gang Zhao, Scott W. Mittelstadt, Bryan F. Cox

Journal:

European Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 325 KB

english, 2010

37

Identification of 2-(4-Benzyloxyphenyl)- N - [1-(2-pyrrolidin-1-yl-ethyl)-1 H -indazol-6-yl]acetamide, an Orally Efficacious Melanin-Concentrating Hormone Receptor 1 Antagonist for the Treatment of Obesity

Souers, Andrew J., Gao, Ju, Brune, Michael, Bush, Eugene, Wodka, Dariusz, Vasudevan, Anil, Judd, Andrew S., Mulhern, Mathew, Brodjian, Sevan, Dayton, Brian, Shapiro, Robin, Hernandez, Lisa E., Marsh,

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 92 KB

english, 2005

38

The Preparation and Utility of Bis(sulfinyl)imidoamidine Ligands for the Copper-Catalyzed Diels−Alder Reaction

Owens, Timothy D., Souers, Andrew J., Ellman, Jonathan A.

Journal:

Journal of Organic Chemistry

Year:

2003

Language:

english

File:

PDF, 301 KB

english, 2003

39

Identification of a Potent Heterocyclic Ligand To Somatostatin Receptor Subtype 5 by the Synthesis and Screening of β-Turn Mimetic Libraries

Souers, Andrew J., Virgilio, Alex A., Rosenquist, Åsa, Fenuik, Wasyl, Ellman, Jonathan A.

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 232 KB

english, 1999

40

Coamplification of miR-4728 protects HER2 -amplified breast cancers from targeted therapy

Floros, Konstantinos V., Lochmann, Timothy L., Hu, Bin, Monterrubio, Carles, Hughes, Mark T., Wells, Jason D., Bernadó Morales, Cristina, Ghotra, Maninderjit S., Costa, Carlotta, Souers, Andrew J., Bo

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.35 MB

english, 2018

41

Inhibition of cyclinâdependent kinase 9 synergistically enhances venetoclax activity in mantle cell lymphoma

Zhao, Xiaoxian, Bodo, Juraj, Chen, Ruoying, Durkin, Lisa, Souers, Andrew J., Phillips, Darren C., Hsi, Eric D.

Journal:

Year:

2020

File:

PDF, 7.70 MB

2020

42

Screening for Cardiovascular Safety: A Structure−Activity Approach for Guiding Lead Selection of Melanin Concentrating Hormone Receptor 1 Antagonists

Kym, Philip R., Souers, Andrew J., Campbell, Thomas J., Lynch, John K., Judd, Andrew S., Iyengar, Rajesh, Vasudevan, Anil, Gao, Ju, Freeman, Jennifer C., Wodka, Dariusz, Mulhern, Mathew, Zhao, Gang, W

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 292 KB

english, 2006

43

Microwave-Assisted C−H Bond Activation: A Rapid Entry into Functionalized Heterocycles

Tan, Kian L., Vasudevan, Anil, Bergman, Robert G., Ellman, Jonathan A., Souers, Andrew J.

Journal:

Organic Letters

Year:

2003

Language:

english

File:

PDF, 72 KB

english, 2003

44

Inhibitors of diacylglycerol acyltransferase: a review of 2008 patents

King, Andrew J, Judd, Andrew S, Souers, Andrew J

Journal:

Expert Opinion on Therapeutic Patents

Year:

2010

Language:

english

File:

PDF, 395 KB

english, 2010

45

Editorial [Hot Topic:Melanin-Concentrating Hormone (MCH) (Guest Editor: Andrew J. Souers)]

Journal:

Current Topics in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 24 KB

english, 2007

46

Validation of Diacyl Glycerolacyltransferase I as a Novel Target for the Treatment of Obesity and Dyslipidemia Using a Potent and Selective Small Molecule Inhibitor

Zhao, Gang, Souers, Andrew J., Voorbach, Martin, Falls, H. Doug, Droz, Brian, Brodjian, Sevan, Lau, Yau Yi, Iyengar, Rajesh R., Gao, Ju, Judd, Andrew S., Wagaw, Seble H., Ravn, Matthew M., Engstrom, K

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 355 KB

english, 2008

47

Genomic analysis and selective small molecule inhibition identifies BCL-XL as a critical survival factor in a subset of colorectal cancer

Zhang, Haichao, Xue, John, Hessler, Paul, Tahir, Stephen K., Chen, Jun, Jin, Sha, Souers, Andrew J., Leverson, Joel D., Lam, Lloyd T.

Journal:

Molecular Cancer

Year:

2015

Language:

english

File:

PDF, 1.78 MB

english, 2015

48

ChemInform Abstract: Optimization of a Somatostatin Mimetic via Constrained Amino Acid and Backbone Incorporation.

Andrew J. Souers, Asa Rosenquist, Emma M. Jarvie, Mark Ladlow, Wasyl Feniuk, Jonathan A. Ellman

Journal:

Year:

2001

File:

PDF, 28 KB

2001

49

ChemInform Abstract: Asymmetric Synthesis of a C-3 Substituted Pipecolic Acid.

Andrew J. Souers, Jonathan A. Ellman

Journal:

Year:

2000

File:

PDF, 27 KB

2000

50

The Preparation and Utility of Bis(sulfinyl)imidoamidine Ligands for the Copper-Catalyzed Diels—Alder Reaction.

Timothy D. Owens, Andrew J. Souers, Jonathan A. Ellman

Journal:

Year:

2003

File:

PDF, 345 KB

2003

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